Research workbench

Streptococcus pneumoniae phosphomevalonate kinase in complex with phosphomevalonate and amppnp

Analyse Streptococcus pneumoniae phosphomevalonate kinase in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3GON
Type: protein
Length: 329 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Phosphomevalonate kinase
EC: 2.7.4.2
UniProt: Q8DR49
Ligands: PMV, ANP, MG
Pockets: 1 · best druggability 0.75

Structure

x-ray diffraction · 1 distinct chain · 43% helix, 23% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Phosphomevalonate kinase (EC 2.7.4.2)	protein	329	43% helix, 23% strand	Q8DR49

Ligands and binding sites

PMV · (3R)-3-hydroxy-3-methyl-5-(phosphonooxy)pentanoic acid · ligand · chains A
ANP · Phosphoaminophosphonic acid-adenylate ester · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	464	0.75	0.84	51	PMV, ANP, MG

Compared structures

3GON · Streptococcus pneumoniae Phosphomevalonate Kinase in Complex with Phosphomevalonate and… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8DR49
Elsewhere: RCSB PDB 3GON · PDBe 3GON · UniProt Q8DR49

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.