Research workbench
Crystal structure of the laminin-binding protein lbp of streptococcus pyogenes
Analyse Crystal structure of the laminin-binding protein lbp of streptococcus pyogenes in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3GI1
- Type
- protein
- Length
- 508 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Laminin-binding protein of group a streptococci
- UniProt
- Q7DII5
- Ligands
- ZN
- Pockets
- 3 · best druggability 0.66
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Laminin-binding protein of group a streptococci | protein | 254 | 45% helix, 15% strand | Q7DII5 |
| B | Laminin-binding protein of group a streptococci | protein | 254 | 46% helix, 15% strand | Q7DII5 |
Ligands and binding sites
- ZN · Zinc ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 561 | 0.66 | 0.77 | 69 | empty |
| 2 | 206 | 0.46 | 0.74 | 26 | empty |
| 3 | 76 | 0.33 | 0.75 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 450 Ų buried · 8 hydrogen bonds · protein-protein
Compared structures
- 3GI1 · Crystal Structure of the laminin-binding protein Lbp of Streptococcus pyogenes · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7DII5
- Elsewhere: RCSB PDB 3GI1 · PDBe 3GI1 · UniProt Q7DII5
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.