Research workbench
Crystal structure of ST1710 complexed with its promoter DNA
Analyse Crystal structure of ST1710 complexed with its promoter DNA in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3GFI
- Type
- protein + DNA
- Length
- 308 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 146AA long hypothetical transcriptional regulator…
- UniProt
- Q96ZY1
- Pockets
- 4 · best druggability 0.66
Structure
x-ray diffraction · 4 distinct chains · 71% helix, 10% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 146AA long hypothetical transcriptional regulator | protein | 143 | 71% helix, 12% strand | Q96ZY1 |
| C | 146AA long hypothetical transcriptional regulator | protein | 142 | 71% helix, 8% strand | Q96ZY1 |
| D | 5'-D(*TP*AP*AP*CP*AP*AP*TP*AP*GP*CP*AP*AP*A)-3' | dna | 13 | — | — |
| E | 5'-D(*TP*TP*GP*CP*TP*AP*TP*TP*GP*T)-3' | dna | 10 | — | — |
Pockets
4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 543 | 0.66 | 0.77 | 40 | empty |
| 2 | 90 | 0.32 | 0.74 | 18 | empty |
| 3 | 55 | 0.30 | 0.76 | 12 | empty |
| 4 | 54 | 0.29 | 0.76 | 11 | empty |
Interfaces
4 interfaces between chains.
- A–C · 2923 Ų buried · 26 hydrogen bonds · protein-protein
- D–E · 444 Ų buried · 42 hydrogen bonds · nucleic-nucleic
- A–D · 223 Ų buried · 3 hydrogen bonds · protein-nucleic
- A–E · 196 Ų buried · 1 hydrogen bond · protein-nucleic
Compared structures
- 3GFI · Crystal structure of ST1710 complexed with its promoter DNA · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q96ZY1
- Elsewhere: RCSB PDB 3GFI · PDBe 3GFI · UniProt Q96ZY1
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