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Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation

Analyse Crystal structure of dengue virus type 1 envelope protein in the postfusion… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3G7T
Type: protein
Length: 379 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Envelope protein
UniProt: Q5USP2
Ligands: CL
Pockets: 4 · best druggability 0.64

Structure

x-ray diffraction · 1 distinct chain · 6% helix, 49% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Envelope protein	protein	379	6% helix, 49% strand	Q5USP2

Ligands and binding sites

CL · Chloride ion · ion

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	326	0.64	0.80	37	empty
2	131	0.52	0.80	23	empty
3	126	0.41	0.75	27	empty
4	96	0.35	0.74	17	empty

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

3G7T · Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5USP2
Elsewhere: RCSB PDB 3G7T · PDBe 3G7T · UniProt Q5USP2

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