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Crystal structure (monoclinic) of bee venom hyaluronidase

Analyse Crystal structure (monoclinic) of bee venom hyaluronidase in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1FCQ
Type: protein
Length: 314 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Hyaluronoglucosaminidase
EC: 3.2.1.35
UniProt: Q08169
Pockets: 2 · best druggability 0.53

Structure

x-ray diffraction · 1 distinct chain · 48% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Hyaluronoglucosaminidase (EC 3.2.1.35)	protein	314	48% helix, 15% strand	Q08169

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	203	0.53	0.77	27	empty
2	64	0.32	0.76	18	empty

Modifications

Observed in the structure: 2 disulfide (disulfide).

Compared structures

1FCQ · Crystal structure (monoclinic) of bee venom hyaluronidase · the same entry in another collection · chain A against A, TM-score 1.00
Q08169 · AlphaFold monomer V2.0 prediction for hyaluronidase (Q08169) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q08169
Elsewhere: RCSB PDB 1FCQ · PDBe 1FCQ · UniProt Q08169

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