Research workbench
Crystal structure of a two-domain protein containing dj-1/THIJ/PFPI- like and ferritin-like domains (AVA_4496) from anabaena variabilis atcc 29413 at 1.90 a resolution
Analyse Crystal structure of a two-domain protein containing dj-1/THIJ/PFPI- like and… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FSE
- Type
- protein
- Length
- 686 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Two-domain protein containing dj-1/THIJ/PFPI-like and ferritin-like domains
- UniProt
- Q3M4J2
- Pockets
- 8 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 53% helix, 12% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Two-domain protein containing dj-1/THIJ/PFPI-like and ferritin-like domains | protein | 337 | 53% helix, 12% strand | Q3M4J2 |
| B | Two-domain protein containing dj-1/THIJ/PFPI-like and ferritin-like domains | protein | 349 | 53% helix, 11% strand | Q3M4J2 |
Ligands and binding sites
- EDO · 1,2-ethanediol · additive · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
8 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1090 | 0.78 | 0.80 | 109 | EDO |
| 2 | 90 | 0.55 | 0.85 | 24 | empty |
| 3 | 53 | 0.46 | 0.84 | 21 | empty |
| 4 | 68 | 0.41 | 0.80 | 16 | empty |
| 5 | 91 | 0.33 | 0.74 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 1720 Ų buried · 27 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 18 modified (engineered, oxidation).
Compared structures
- 3FSE · Crystal structure of a two-domain protein containing dj-1/thij/pfpi-like and… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3M4J2
- Elsewhere: RCSB PDB 3FSE · PDBe 3FSE · UniProt Q3M4J2
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