Research workbench
Dimeric structure of pd-L1
Analyse Dimeric structure of pd-L1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FN3
- Type
- protein
- Length
- 426 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Programmed cell death 1 ligand 1
- UniProt
- Q9NZQ7
- Pockets
- 6 · best druggability 0.74
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 54% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Programmed cell death 1 ligand 1 | protein | 215 | 6% helix, 53% strand | Q9NZQ7 |
| B | Programmed cell death 1 ligand 1 | protein | 211 | 3% helix, 54% strand | Q9NZQ7 |
Pockets
6 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 823 | 0.74 | 0.79 | 74 | empty |
| 2 | 78 | 0.41 | 0.79 | 14 | empty |
| 3 | 61 | 0.37 | 0.79 | 15 | empty |
| 4 | 95 | 0.34 | 0.73 | 17 | empty |
| 5 | 84 | 0.33 | 0.74 | 13 | empty |
Interfaces
1 interface between chains.
- A–B · 1106 Ų buried · 9 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 3FN3 · Dimeric Structure of PD-L1 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NZQ7
- Elsewhere: RCSB PDB 3FN3 · PDBe 3FN3 · UniProt Q9NZQ7
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