Research workbench

Rifr - type II thioesterase from rifamycin NRPS/PKS biosynthetic pathway - form 2

Analyse Rifr - type II thioesterase from rifamycin NRPS/PKS biosynthetic pathway - form… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3FLB
Type: protein
Length: 245 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Rifr
EC: 3.1.2.-
UniProt: Q7BUF9
Ligands: CL
Pockets: 1 · best druggability 0.54

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Rifr (EC 3.1.2.-)	protein	245	47% helix, 16% strand	Q7BUF9

Ligands and binding sites

CL · Chloride ion · ion · chains A
PG4 · Tetraethylene glycol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	88	0.54	0.84	14	PG4

Compared structures

3FLB · RifR - Type II thioesterase from Rifamycin NRPS/PKS biosynthetic pathway - Form 2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q7BUF9
Elsewhere: RCSB PDB 3FLB · PDBe 3FLB · UniProt Q7BUF9

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.