Research workbench
Crystal structure of a uncharacterized protein LIN1909
Analyse Crystal structure of a uncharacterized protein LIN1909 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FIJ
- Type
- protein
- Length
- 1,783 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- LIN1909 protein
- UniProt
- Q92AL3
- Ligands
- MN
- Pockets
- 9 · best druggability 0.48
Structure
x-ray diffraction · 5 distinct chains · 32% helix, 22% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, E, H | LIN1909 protein | protein | 224 | 33% helix, 22% strand | Q92AL3 |
| B | LIN1909 protein | protein | 222 | 31% helix, 23% strand | Q92AL3 |
| C | LIN1909 protein | protein | 221 | 33% helix, 23% strand | Q92AL3 |
| D, F | LIN1909 protein | protein | 223 | 32% helix, 22% strand | Q92AL3 |
| G | LIN1909 protein | protein | 222 | 31% helix, 21% strand | Q92AL3 |
Ligands and binding sites
- MN · Manganese (II) ion · metal · 8 copies · chains A, B, C, D, E, F, G, H
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
9 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 173 | 0.48 | 0.77 | 29 | empty |
| 2 | 213 | 0.47 | 0.74 | 30 | empty |
| 3 | 185 | 0.46 | 0.75 | 25 | empty |
| 4 | 173 | 0.44 | 0.74 | 25 | empty |
| 5 | 55 | 0.32 | 0.77 | 17 | empty |
Interfaces
12 interfaces between chains.
- G–H · 888 Ų buried · 9 hydrogen bonds · protein-protein
- E–F · 882 Ų buried · 9 hydrogen bonds · protein-protein
- B–D · 845 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 827 Ų buried · 10 hydrogen bonds · protein-protein
- C–G · 608 Ų buried · 7 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 27 modified (engineered).
Compared structures
- 3FIJ · Crystal structure of a uncharacterized protein lin1909 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q92AL3
- Elsewhere: RCSB PDB 3FIJ · PDBe 3FIJ · UniProt Q92AL3
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