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Lpxr from salmonella typhimurium

Analyse Lpxr from salmonella typhimurium in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3FID
Type: protein
Length: 592 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative outer membrane protein (lpxr)
UniProt: Q8ZPT3
Ligands: CXE, ZN
Pockets: 9 · best druggability 0.83

Structure

x-ray diffraction · 1 distinct chain · 18% helix, 53% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Putative outer membrane protein (lpxr)	protein	296	18% helix, 53% strand	Q8ZPT3

Ligands and binding sites

CXE · Pentaethylene glycol monodecyl ether · ligand · 8 copies · chains A, B
ZN · Zinc ion · metal · 9 copies · chains A, B
GOL · Glycerol · additive · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

9 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	192	0.83	0.97	40	GOL
2	187	0.82	0.96	42	GOL
3	117	0.80	0.99	23	empty
4	105	0.77	0.97	23	empty
5	969	0.73	0.77	65	GOL, ZN

Interfaces

1 interface between chains.

A–B · 742 Å² buried · 9 hydrogen bonds · protein-protein

Compared structures

3FID · LpxR from Salmonella typhimurium · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8ZPT3
Elsewhere: RCSB PDB 3FID · PDBe 3FID · UniProt Q8ZPT3

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