Research workbench
Crystal structure of a putative antibiotic biosynthesis monooxygenase (SPO2313) from silicibacter pomeroyi dss-3 at 1.30 a resolution
Analyse Crystal structure of a putative antibiotic biosynthesis monooxygenase (SPO2313)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FGV
- Type
- protein
- Length
- 188 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein with ferredoxin-like fold
- UniProt
- Q5LR19
- Ligands
- UNL
- Pockets
- 3 · best druggability 0.60
Structure
x-ray diffraction · 1 distinct chain · 41% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Uncharacterized protein with ferredoxin-like fold | protein | 94 | 41% helix, 35% strand | Q5LR19 |
Ligands and binding sites
- UNL · Unknown ligand · ion · 11 copies · chains A, B
- EDO · 1,2-ethanediol · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 93 | 0.60 | 0.87 | 20 | UNL |
| 2 | 116 | 0.58 | 0.84 | 16 | empty |
| 3 | 90 | 0.56 | 0.85 | 20 | UNL |
Interfaces
1 interface between chains.
- A–B · 868 Ų buried · 15 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3FGV · Crystal structure of a putative antibiotic biosynthesis monooxygenase (SPO2313) from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5LR19
- Elsewhere: RCSB PDB 3FGV · PDBe 3FGV · UniProt Q5LR19
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