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Structure of nk cell receptor KLRG1

Analyse Structure of nk cell receptor KLRG1 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3FF9
Type: protein
Length: 230 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Killer cell lectin-like receptor subfamily G member 1
UniProt: O88713
Pockets: 1 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 13% helix, 36% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Killer cell lectin-like receptor subfamily G member 1	protein	115	13% helix, 36% strand	O88713

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	330	0.70	0.83	56	empty

Interfaces

1 interface between chains.

A–B · 543 Å² buried · 8 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 6 disulfide (disulfide).

Compared structures

3FF9 · Structure of NK cell receptor KLRG1 · the same entry in another collection · chain A against A, TM-score 1.00
O88713 · AlphaFold monomer V2.0 prediction for killer cell lectin-like receptor subfamily G member… · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O88713
Elsewhere: RCSB PDB 3FF9 · PDBe 3FF9 · UniProt O88713

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