Research workbench
Crystal structure of the transcriptional anti-activator exsd from pseudomonas aeruginosa
Analyse Crystal structure of the transcriptional anti-activator exsd from pseudomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FD9
- Type
- protein
- Length
- 718 residues
- Chains
- 3
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q02KK5
- Pockets
- 10 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 70% helix, 3% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 240 | 70% helix, 3% strand | Q02KK5 |
| B, C | Uncharacterized protein | protein | 239 | 71% helix, 3% strand | Q02KK5 |
Pockets
10 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 497 | 0.78 | 0.85 | 51 | empty |
| 2 | 628 | 0.75 | 0.81 | 60 | empty |
| 3 | 573 | 0.74 | 0.81 | 53 | empty |
| 4 | 489 | 0.69 | 0.80 | 49 | empty |
| 5 | 233 | 0.64 | 0.83 | 36 | empty |
Interfaces
3 interfaces between chains.
- A–B · 1354 Ų buried · 11 hydrogen bonds · protein-protein
- A–C · 1299 Ų buried · 7 hydrogen bonds · protein-protein
- B–C · 1256 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 9 modified (engineered).
Compared structures
- 3FD9 · Crystal Structure of the transcriptional anti-activator ExsD from Pseudomonas aeruginosa · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q02KK5
- Elsewhere: RCSB PDB 3FD9 · PDBe 3FD9 · UniProt Q02KK5
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