Research workbench
Crystal structure of a chorismate MUTASE/SHIKIMATE 5-dehydrogenase fusion protein from clostridium acetobutylicum
Analyse Crystal structure of a chorismate MUTASE/SHIKIMATE 5-dehydrogenase fusion… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3FBT
- Type
- protein
- Length
- 1,081 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Chorismate mutase and shikimate 5-dehydrogenase fusion protein
- EC
- 5.4.99.5, 1.1.1.25
- UniProt
- Q97KM0
- Ligands
- SO4
- Pockets
- 14 · best druggability 0.70
Structure
x-ray diffraction · 3 distinct chains · 41% helix, 20% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, D | Chorismate mutase and shikimate 5-dehydrogenase fusion protein (EC 5.4.99.5, 1.1.1.25) | protein | 272 | 42% helix, 20% strand | Q97KM0 |
| B | Chorismate mutase and shikimate 5-dehydrogenase fusion protein (EC 5.4.99.5, 1.1.1.25) | protein | 267 | 40% helix, 20% strand | Q97KM0 |
| C | Chorismate mutase and shikimate 5-dehydrogenase fusion protein (EC 5.4.99.5, 1.1.1.25) | protein | 270 | 42% helix, 21% strand | Q97KM0 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 9 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
14 pockets found on a 1 Å grid, 5 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 499 | 0.70 | 0.80 | 38 | empty |
| 2 | 471 | 0.70 | 0.80 | 35 | empty |
| 3 | 496 | 0.70 | 0.80 | 37 | empty |
| 4 | 430 | 0.69 | 0.81 | 35 | empty |
| 5 | 282 | 0.51 | 0.74 | 28 | empty |
Interfaces
3 interfaces between chains.
- A–B · 870 Ų buried · 10 hydrogen bonds · protein-protein
- C–D · 857 Ų buried · 13 hydrogen bonds · protein-protein
- B–D · 212 Ų buried · 1 hydrogen bond · protein-protein
Compared structures
- 3FBT · Crystal structure of a chorismate mutase/shikimate 5-dehydrogenase fusion protein from… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q97KM0
- Elsewhere: RCSB PDB 3FBT · PDBe 3FBT · UniProt Q97KM0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.