Research workbench
Crystal structure of ahrc, the arginine REPRESSOR/ACTIVATOR protein from bacillus subtilis
Analyse Crystal structure of ahrc, the arginine REPRESSOR/ACTIVATOR protein from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1F9N
- Type
- protein
- Length
- 887 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Arginine REPRESSOR/ACTIVATOR protein
- UniProt
- P17893
- Pockets
- 12 · best druggability 0.80
Structure
x-ray diffraction · 4 distinct chains · 44% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Arginine REPRESSOR/ACTIVATOR protein | protein | 147 | 45% helix, 22% strand | P17893 |
| B, F | Arginine REPRESSOR/ACTIVATOR protein | protein | 149 | 43% helix, 21% strand | P17893 |
| C, E | Arginine REPRESSOR/ACTIVATOR protein | protein | 148 | 44% helix, 21% strand | P17893 |
| D | Arginine REPRESSOR/ACTIVATOR protein | protein | 146 | 42% helix, 21% strand | P17893 |
Pockets
12 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 895 | 0.80 | 0.83 | 121 | empty |
| 2 | 415 | 0.66 | 0.79 | 27 | empty |
| 3 | 192 | 0.63 | 0.84 | 33 | empty |
| 4 | 240 | 0.59 | 0.80 | 40 | empty |
| 5 | 88 | 0.48 | 0.82 | 21 | empty |
Interfaces
14 interfaces between chains.
- B–E · 1178 Ų buried · 17 hydrogen bonds · protein-protein
- A–F · 964 Ų buried · 6 hydrogen bonds · protein-protein
- C–D · 886 Ų buried · 6 hydrogen bonds · protein-protein
- A–B · 466 Ų buried · 2 hydrogen bonds · protein-protein
- D–F · 443 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 1F9N · Crystal structure of ahrc, the arginine REPRESSOR/ACTIVATOR protein from bacillus subtilis · the same entry in another collection · chain F against F, TM-score 1.00
- P17893 · AlphaFold monomer V2.0 prediction for arginine repressor (P17893) · a predicted model of the same protein · chain D against A, TM-score 0.61
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P17893
- Elsewhere: RCSB PDB 1F9N · PDBe 1F9N · UniProt P17893
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.