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Structure of orthorhombic crystal form of pseudomonas aeruginosa rssb

Analyse Structure of orthorhombic crystal form of pseudomonas aeruginosa rssb in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3F7A
Type: protein
Length: 750 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Probable two-component response regulator
UniProt: Q9I045
Pockets: 9 · best druggability 0.76

Structure

x-ray diffraction · 2 distinct chains · 34% helix, 16% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Probable two-component response regulator	protein	372	33% helix, 15% strand	Q9I045
B	Probable two-component response regulator	protein	378	35% helix, 16% strand	Q9I045

Pockets

9 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	335	0.76	0.87	57	empty
2	546	0.73	0.81	54	empty
3	288	0.72	0.86	33	empty
4	626	0.72	0.79	46	empty
5	59	0.70	0.97	19	empty

Interfaces

1 interface between chains.

A–B · 2297 Å² buried · 16 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 12 modified (engineered).

Compared structures

3F7A · Structure of Orthorhombic crystal form of Pseudomonas aeruginosa RssB · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9I045
Elsewhere: RCSB PDB 3F7A · PDBe 3F7A · UniProt Q9I045

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