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Crystal structure of putative short chain dehydrogenase from escherichia COLI CFT073

Analyse Crystal structure of putative short chain dehydrogenase from escherichia COLI… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3F5Q
Type: protein
Length: 457 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dehydrogenase
EC: 1.-.-.-
UniProt: Q8FHV3
Pockets: 4 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 46% helix, 15% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Dehydrogenase (EC 1.-.-.-)	protein	228	46% helix, 15% strand	Q8FHV3
B	Dehydrogenase (EC 1.-.-.-)	protein	229	46% helix, 15% strand	Q8FHV3

Pockets

4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	334	0.59	0.77	39	empty
2	338	0.58	0.76	40	empty
3	167	0.45	0.74	23	empty
4	132	0.43	0.76	25	empty

Interfaces

1 interface between chains.

A–B · 296 Å² buried · 8 hydrogen bonds · protein-protein

Compared structures

3F5Q · CRYSTAL STRUCTURE OF putative short chain dehydrogenase from Escherichia coli CFT073 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8FHV3
Elsewhere: RCSB PDB 3F5Q · PDBe 3F5Q · UniProt Q8FHV3

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