Research workbench
HIV GP41 six-helix bundle containing a mutant chr alpha- peptide sequence
Analyse HIV GP41 six-helix bundle containing a mutant chr alpha- peptide sequence in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3F4Y
- Type
- protein
- Length
- 222 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Envelope glycoprotein GP160; Mutant peptide derived from HIV GP41 chr domain
- UniProt
- P04580
- Ligands
- ACE, NH2
Structure
x-ray diffraction · 2 distinct chains · 89% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | Envelope glycoprotein GP160 | protein | 36 | 94% helix, 0% strand | P04580 |
| D, E, F | Mutant peptide derived from HIV GP41 chr domain | protein | 38 | 84% helix, 0% strand | — |
Ligands and binding sites
- ACE · Acetyl group · ligand · 6 copies · chains A, E, B, F, C, D
- NH2 · Amino group · ion · 6 copies · chains A, B, C, D, E, F
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Interfaces
9 interfaces between chains.
- A–D · 793 Ų buried · 12 hydrogen bonds · protein-protein
- C–F · 785 Ų buried · 8 hydrogen bonds · protein-protein
- B–E · 758 Ų buried · 5 hydrogen bonds · protein-protein
- A–C · 701 Ų buried · 8 hydrogen bonds · protein-protein
- A–B · 676 Ų buried · 4 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 covalent (covalent ligand).
Compared structures
- 3F4Y · HIV gp41 six-helix bundle containing a mutant CHR alpha-peptide sequence · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P04580
- Elsewhere: RCSB PDB 3F4Y · PDBe 3F4Y · UniProt P04580
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