Research workbench
Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from listeria monocytogenes
Analyse Crystal structure of 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3F1C
- Type
- protein
- Length
- 459 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2
- EC
- 2.7.7.60
- UniProt
- Q720Y7
- Pockets
- 1 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 41% helix, 24% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 (EC 2.7.7.60) | protein | 229 | 41% helix, 24% strand | Q720Y7 |
| B | Putative 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase 2 (EC 2.7.7.60) | protein | 230 | 41% helix, 23% strand | Q720Y7 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 961 | 0.77 | 0.80 | 115 | empty |
Interfaces
1 interface between chains.
- A–B · 1988 Ų buried · 22 hydrogen bonds · protein-protein
Compared structures
- 3F1C · CRYSTAL STRUCTURE OF 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase from… · the same entry in another collection · chain A against A, TM-score 1.00
- Q720Y7 · AlphaFold monomer V2.0 prediction for ribitol-5-phosphate cytidylyltransferase (Q720Y7) · a predicted model of the same protein · chain A against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q720Y7
- Elsewhere: RCSB PDB 3F1C · PDBe 3F1C · UniProt Q720Y7
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