Research workbench
The crystal structure of the transcriptional regulator, tetr family from cytophaga hutchinsonii
Analyse The crystal structure of the transcriptional regulator, tetr family from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3EUP
- Type
- protein
- Length
- 403 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, tetr family
- UniProt
- Q11R54
- Ligands
- SO4
- Pockets
- 5 · best druggability 0.78
Structure
x-ray diffraction · 2 distinct chains · 75% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, tetr family | protein | 203 | 75% helix, 1% strand | Q11R54 |
| B | Transcriptional regulator, tetr family | protein | 200 | 75% helix, 1% strand | Q11R54 |
Ligands and binding sites
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 169 | 0.78 | 0.94 | 44 | empty |
| 2 | 86 | 0.51 | 0.83 | 24 | empty |
| 3 | 94 | 0.50 | 0.81 | 26 | empty |
| 4 | 166 | 0.49 | 0.77 | 26 | empty |
| 5 | 53 | 0.30 | 0.76 | 15 | empty |
Interfaces
1 interface between chains.
- A–B · 1837 Ų buried · 16 hydrogen bonds · protein-protein
Compared structures
- 3EUP · The crystal structure of the transcriptional regulator, TetR family from Cytophaga… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q11R54
- Elsewhere: RCSB PDB 3EUP · PDBe 3EUP · UniProt Q11R54
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.