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The crystal structure of putative zinc protease beta- subunit from thermus thermophilus HB8

Analyse The crystal structure of putative zinc protease beta- subunit from thermus… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3EOQ
Type: protein
Length: 811 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative zinc protease
EC: 3.4.24.56
UniProt: Q5SIV0
Pockets: 6 · best druggability 0.67

Structure

x-ray diffraction · 2 distinct chains · 48% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative zinc protease (EC 3.4.24.56)	protein	405	49% helix, 19% strand	Q5SIV0
B	Putative zinc protease (EC 3.4.24.56)	protein	406	48% helix, 19% strand	Q5SIV0

Pockets

6 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	614	0.67	0.76	61	empty
2	596	0.66	0.76	60	empty
3	391	0.66	0.80	39	empty
4	158	0.48	0.77	22	empty
5	158	0.44	0.75	28	empty

Interfaces

1 interface between chains.

A–B · 1010 Å² buried · 4 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 18 modified (engineered).

Compared structures

3EOQ · The crystal structure of putative zinc protease beta-subunit from Thermus thermophilus HB8 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q5SIV0
Elsewhere: RCSB PDB 3EOQ · PDBe 3EOQ · UniProt Q5SIV0

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