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Crystal structure of the dnac helicase loader in complex with ADP-BEF3

Analyse Crystal structure of the dnac helicase loader in complex with ADP-BEF3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ECC
Type: protein
Length: 182 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: DNA replication protein dnac
UniProt: O67056
Ligands: ADP, BEF, MG
Pockets: 3 · best druggability 0.40

Structure

x-ray diffraction · 1 distinct chain · 47% helix, 14% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	DNA replication protein dnac	protein	182	47% helix, 14% strand	O67056

Ligands and binding sites

ADP · Adenosine-5'-diphosphate · ligand · chains A
BEF · Beryllium trifluoride ion · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	126	0.40	0.75	23	ADP, MG, BEF
2	87	0.34	0.74	13	empty
3	52	0.31	0.77	16	empty

Compared structures

3ECC · Crystal structure of the DnaC helicase loader in complex with ADP-BeF3 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O67056
Elsewhere: RCSB PDB 3ECC · PDBe 3ECC · UniProt O67056

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