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Crystal structure of major allergens, bla G 4 from cockroaches
Analyse Crystal structure of major allergens, bla G 4 from cockroaches in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3EBK
- Type
- protein
- Length
- 329 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Allergen bla G 4
- UniProt
- P54962
- Pockets
- 5 · best druggability 0.77
Structure
x-ray diffraction · 2 distinct chains · 23% helix, 38% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Allergen bla G 4 | protein | 165 | 24% helix, 38% strand | P54962 |
| B | Allergen bla G 4 | protein | 164 | 23% helix, 38% strand | P54962 |
Pockets
5 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 78 | 0.77 | 0.99 | 17 | empty |
| 2 | 68 | 0.76 | 0.99 | 18 | empty |
| 3 | 119 | 0.46 | 0.78 | 20 | empty |
| 4 | 120 | 0.38 | 0.74 | 33 | empty |
| 5 | 52 | 0.26 | 0.74 | 10 | empty |
Interfaces
1 interface between chains.
- A–B · 640 Ų buried · 13 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P54962
- Elsewhere: RCSB PDB 3EBK · PDBe 3EBK · UniProt P54962
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