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Crystal structure of putative SAM dependent methyltransferase in complex with sah (NP_744700.1) from pseudomonas putida KT2440 at 2.10 a resolution

Analyse Crystal structure of putative SAM dependent methyltransferase in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3E8S
Type: protein
Length: 220 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative SAM dependent methyltransferase
UniProt: Q88JU2
Ligands: SAH
Pockets: 1 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 36% helix, 25% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Putative SAM dependent methyltransferase	protein	220	36% helix, 25% strand	Q88JU2

Ligands and binding sites

SAH · S-adenosyl-L-homocysteine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	426	0.74	0.84	52	SAH

Modifications

Observed in the structure: 4 modified (engineered).

Compared structures

3E8S · Crystal structure of Putative SAM Dependent Methyltransferase in Complex with SAH… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q88JU2
Elsewhere: RCSB PDB 3E8S · PDBe 3E8S · UniProt Q88JU2

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