Research workbench

Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from bartonella henselae

Analyse Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3E60
Type: protein
Length: 840 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: 3-oxoacyl-[acyl-carrier-protein ] synthase II
UniProt: Q6G441
Ligands: K
Pockets: 10 · best druggability 0.77

Structure

x-ray diffraction · 1 distinct chain · 37% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	3-oxoacyl-[acyl-carrier-protein ] synthase II	protein	420	37% helix, 21% strand	Q6G441

Ligands and binding sites

K · Potassium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

10 pockets found on a 1 Å grid, 6 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	85	0.77	0.98	24	empty
2	53	0.72	0.99	17	empty
3	204	0.68	0.86	34	empty
4	215	0.67	0.85	36	empty
5	136	0.55	0.82	19	empty

Interfaces

1 interface between chains.

A–B · 3052 Å² buried · 43 hydrogen bonds · protein-protein

Compared structures

3E60 · Crystal structure of 3-oxoacyl-(acyl carrier protein) synthase II from Bartonella henselae · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q6G441
Elsewhere: RCSB PDB 3E60 · PDBe 3E60 · UniProt Q6G441

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.