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X-ray structure of the putative gluconolactonase in protein family PF08450. northeast structural genomics consortium target DRR130.

Analyse X-ray structure of the putative gluconolactonase in protein family PF08450.… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3E5Z
Type: protein
Length: 580 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Putative gluconolactonase
UniProt: Q9RXN3
Ligands: MG
Pockets: 6 · best druggability 0.74

Structure

x-ray diffraction · 1 distinct chain · 7% helix, 48% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Putative gluconolactonase	protein	290	7% helix, 48% strand	Q9RXN3

Ligands and binding sites

MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	365	0.74	0.85	33	empty
2	339	0.74	0.86	31	empty
3	91	0.41	0.78	21	empty
4	62	0.39	0.80	17	empty
5	51	0.31	0.76	14	empty

Modifications

Observed in the structure: 6 modified (engineered).

Compared structures

3E5Z · X-Ray structure of the putative gluconolactonase in protein family PF08450. Northeast… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9RXN3
Elsewhere: RCSB PDB 3E5Z · PDBe 3E5Z · UniProt Q9RXN3

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