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Crystal structure of ascaris pepsin inhibitor-3

Analyse Crystal structure of ascaris pepsin inhibitor-3 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 1F32
Type: protein
Length: 127 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Major pepsin inhibitor pi-3
UniProt: P19400
Pockets: 1 · best druggability 0.36

Structure

x-ray diffraction · 1 distinct chain · 39% helix, 28% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Major pepsin inhibitor pi-3	protein	127	39% helix, 28% strand	P19400

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	57	0.36	0.78	16	empty

Modifications

Observed in the structure: 3 disulfide (disulfide).

Compared structures

1F32 · Crystal structure of ascaris pepsin inhibitor-3 · the same entry in another collection · chain A against A, TM-score 1.00
P19400 · AlphaFold monomer V2.0 prediction for major pepsin inhibitor 3 (P19400) · a predicted model of the same protein · chain A against A, TM-score 0.97

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P19400
Elsewhere: RCSB PDB 1F32 · PDBe 1F32 · UniProt P19400

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