Research workbench
Structure of DOCH66Y dimer
Analyse Structure of DOCH66Y dimer in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3DD9
- Type
- protein
- Length
- 931 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Death on curing protein
- UniProt
- Q06259
- Pockets
- 9 · best druggability 0.44
Structure
x-ray diffraction · 8 distinct chains · 69% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Death on curing protein | protein | 117 | 70% helix, 0% strand | Q06259 |
| B | Death on curing protein | protein | 118 | 69% helix, 0% strand | Q06259 |
| C | Death on curing protein | protein | 115 | 66% helix, 0% strand | Q06259 |
| D | Death on curing protein | protein | 122 | 68% helix, 0% strand | Q06259 |
| E | Death on curing protein | protein | 113 | 66% helix, 0% strand | Q06259 |
| F | Death on curing protein | protein | 110 | 71% helix, 0% strand | Q06259 |
| G | Death on curing protein | protein | 114 | 71% helix, 0% strand | Q06259 |
| H | Death on curing protein | protein | 122 | 70% helix, 0% strand | Q06259 |
Pockets
9 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 171 | 0.44 | 0.74 | 28 | empty |
| 2 | 149 | 0.43 | 0.75 | 24 | empty |
| 3 | 103 | 0.43 | 0.78 | 21 | empty |
| 4 | 102 | 0.41 | 0.77 | 17 | empty |
| 5 | 101 | 0.35 | 0.74 | 19 | empty |
Interfaces
11 interfaces between chains.
- A–B · 2653 Ų buried · 33 hydrogen bonds · protein-protein
- G–H · 2646 Ų buried · 32 hydrogen bonds · protein-protein
- C–D · 2575 Ų buried · 28 hydrogen bonds · protein-protein
- E–F · 2468 Ų buried · 30 hydrogen bonds · protein-protein
- B–H · 371 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 3DD9 · Structure of DocH66Y dimer · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q06259
- Elsewhere: RCSB PDB 3DD9 · PDBe 3DD9 · UniProt Q06259
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