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Crystal structure of gumk mutant D157A

Analyse Crystal structure of gumk mutant D157A in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CUY
Type: protein
Length: 364 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Glucuronosyltransferase gumk
EC: 2.4.1.17
UniProt: Q8GCH2
Pockets: 4 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 40% helix, 19% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Glucuronosyltransferase gumk (EC 2.4.1.17)	protein	364	40% helix, 19% strand	Q8GCH2

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	751	0.76	0.80	60	empty
2	133	0.46	0.77	19	empty
3	52	0.44	0.84	18	empty
4	76	0.40	0.79	16	empty

Compared structures

3CUY · Crystal Structure of GumK mutant D157A · the same entry in another collection · chain A against A, TM-score 1.00
Q8GCH2 · AlphaFold monomer V2.0 prediction for udp-GLUCURONATE:GLYCOLIPID… · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q8GCH2
Elsewhere: RCSB PDB 3CUY · PDBe 3CUY · UniProt Q8GCH2

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