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Crystal structure of dham of L. lactis

Analyse Crystal structure of dham of L. lactis in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CT6
Type: protein
Length: 258 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Pts-dependent dihydroxyacetone kinase, phosphotransferase subunit dham
EC: 2.7.1.-
UniProt: Q9CIV6
Pockets: 2 · best druggability 0.43

Structure

x-ray diffraction · 2 distinct chains · 45% helix, 17% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Pts-dependent dihydroxyacetone kinase, phosphotransferase subunit dham (EC 2.7.1.-)	protein	130	45% helix, 17% strand	Q9CIV6
B	Pts-dependent dihydroxyacetone kinase, phosphotransferase subunit dham (EC 2.7.1.-)	protein	128	45% helix, 18% strand	Q9CIV6

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	98	0.43	0.78	14	empty
2	79	0.40	0.78	19	empty

Interfaces

1 interface between chains.

A–B · 1218 Å² buried · 20 hydrogen bonds · protein-protein

Compared structures

3CT6 · Crystal structure of DhaM of L. lactis · the same entry in another collection · chain A against A, TM-score 1.00
Q9CIV6 · AlphaFold monomer V2.0 prediction for pts-dependent dihydroxyacetone kinase… · a predicted model of the same protein · chain B against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9CIV6
Elsewhere: RCSB PDB 3CT6 · PDBe 3CT6 · UniProt Q9CIV6

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