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Crystal structure of muconate cycloisomerase from pseudomonas fluorescens

Analyse Crystal structure of muconate cycloisomerase from pseudomonas fluorescens in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CT2
Type: protein
Length: 722 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Muconate cycloisomerase
EC: 5.5.1.1
UniProt: Q4K9X1
Ligands: MG
Pockets: 3 · best druggability 0.78

Structure

x-ray diffraction · 1 distinct chain · 42% helix, 21% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Muconate cycloisomerase (EC 5.5.1.1)	protein	361	42% helix, 21% strand	Q4K9X1

Ligands and binding sites

MG · Magnesium ion · metal · 2 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	776	0.78	0.82	74	empty
2	182	0.55	0.79	44	empty
3	148	0.53	0.80	31	empty

Interfaces

1 interface between chains.

A–B · 1285 Å² buried · 19 hydrogen bonds · protein-protein

Compared structures

3CT2 · Crystal structure of muconate cycloisomerase from Pseudomonas fluorescens · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4K9X1
Elsewhere: RCSB PDB 3CT2 · PDBe 3CT2 · UniProt Q4K9X1

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