Research workbench
Structure of the serratia marcescens hemophore receptor hasr in complex with its hemophore hasa
Analyse Structure of the serratia marcescens hemophore receptor hasr in complex with… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3CSN
- Type
- protein
- Length
- 1,832 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Hasr protein; Hemophore hasa
- UniProt
- Q79AD2, Q54450
- Pockets
- 20 · best druggability 0.82
Structure
x-ray diffraction · 2 distinct chains · 10% helix, 48% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Hasr protein | protein | 753 | 6% helix, 50% strand | Q79AD2 |
| C, D | Hemophore hasa | protein | 163 | 29% helix, 36% strand | Q54450 |
Ligands and binding sites
- GOL · Glycerol · additive · 5 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
20 pockets found on a 1 Å grid, 9 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1057 | 0.82 | 0.83 | 103 | empty |
| 2 | 953 | 0.81 | 0.83 | 95 | empty |
| 3 | 90 | 0.77 | 0.98 | 36 | empty |
| 4 | 94 | 0.76 | 0.97 | 38 | empty |
| 5 | 539 | 0.74 | 0.82 | 67 | empty |
Interfaces
2 interfaces between chains.
- A–C · 1904 Ų buried · 23 hydrogen bonds · protein-protein
- B–D · 1874 Ų buried · 19 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 4 disulfide (disulfide).
Compared structures
- 3CSN · Structure of the Serratia marcescens hemophore receptor HasR in complex with its… · the same entry in another collection · chain A against A, TM-score 1.00
- Q54450 · AlphaFold monomer V2.0 prediction for hemophore hasa (Q54450) · a predicted model of the same protein · chain C against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q79AD2
- Every structure of UniProt Q54450
- Elsewhere: RCSB PDB 3CSN · PDBe 3CSN · UniProt Q79AD2 · UniProt Q54450
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.