Research workbench
XPD_HELICASE
Analyse XPD_HELICASE in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3CRV
- Type
- protein
- Length
- 551 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- XPD/RAD3 related DNA helicase
- EC
- 3.-.-.-
- UniProt
- Q4JC68
- Ligands
- SF4
- Pockets
- 4 · best druggability 0.84
Structure
x-ray diffraction · 1 distinct chain · 43% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | XPD/RAD3 related DNA helicase (EC 3.-.-.-) | protein | 551 | 43% helix, 17% strand | Q4JC68 |
Ligands and binding sites
- SF4 · Iron/sulfur cluster · ligand · chains A
- IPA · Isopropyl alcohol · additive · 7 copies · chains A
- FLC · Citrate anion · additive · chains A
- GOL · Glycerol · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1134 | 0.84 | 0.85 | 133 | IPA |
| 2 | 201 | 0.52 | 0.77 | 22 | IPA, GOL |
| 3 | 86 | 0.35 | 0.75 | 22 | empty |
| 4 | 64 | 0.29 | 0.74 | 16 | empty |
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q4JC68
- Elsewhere: RCSB PDB 3CRV · PDBe 3CRV · UniProt Q4JC68
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.