Research workbench
Crystal structure of anthrolysin O (alo)
Analyse Crystal structure of anthrolysin O (alo) in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3CQF
- Type
- protein
- Length
- 924 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Thiol-activated cytolysin
- UniProt
- Q81N62
- Pockets
- 9 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 19% helix, 35% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Thiol-activated cytolysin | protein | 462 | 19% helix, 35% strand | Q81N62 |
Pockets
9 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 107 | 0.57 | 0.85 | 20 | empty |
| 2 | 133 | 0.57 | 0.83 | 24 | empty |
| 3 | 148 | 0.56 | 0.82 | 27 | empty |
| 4 | 116 | 0.55 | 0.83 | 21 | empty |
| 5 | 99 | 0.42 | 0.77 | 22 | empty |
Interfaces
1 interface between chains.
- A–B · 436 Ų buried · 3 hydrogen bonds · protein-protein
Compared structures
- 3CQF · Crystal structure of anthrolysin O (ALO) · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q81N62
- Elsewhere: RCSB PDB 3CQF · PDBe 3CQF · UniProt Q81N62
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