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The crystal structure of corynebacterium glutamicum dihydrodipicolinate synthase to 2.2 a resolution

Analyse The crystal structure of corynebacterium glutamicum dihydrodipicolinate… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CPR
Type: protein
Length: 604 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Dihydrodipicolinate synthetase
EC: 4.2.1.52
UniProt: Q546B6
Pockets: 3 · best druggability 0.69

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 13% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Dihydrodipicolinate synthetase (EC 4.2.1.52)	protein	302	50% helix, 13% strand	Q546B6

Pockets

3 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	443	0.69	0.80	52	empty
2	198	0.57	0.80	42	empty
3	173	0.54	0.80	38	empty

Interfaces

1 interface between chains.

A–B · 1272 Å² buried · 14 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (nonstandard).

Compared structures

3CPR · The crystal structure of Corynebacterium glutamicum dihydrodipicolinate synthase to 2.2 A… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q546B6
Elsewhere: RCSB PDB 3CPR · PDBe 3CPR · UniProt Q546B6

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