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Crystal structure of the DBL3X domain of the plasmodium falcipurum VAR2CSA protein
Analyse Crystal structure of the DBL3X domain of the plasmodium falcipurum VAR2CSA… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3CML
- Type
- protein
- Length
- 317 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Erythrocyte membrane protein 1
- UniProt
- Q6UDW7
- Pockets
- 3 · best druggability 0.52
Structure
x-ray diffraction · 1 distinct chain · 55% helix, 2% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Erythrocyte membrane protein 1 | protein | 317 | 55% helix, 2% strand | Q6UDW7 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 106 | 0.52 | 0.82 | 28 | empty |
| 2 | 115 | 0.39 | 0.74 | 19 | empty |
| 3 | 67 | 0.38 | 0.79 | 15 | empty |
Modifications
Observed in the structure: 6 disulfide (disulfide).
Compared structures
- 3CML · Crystal Structure of the DBL3x domain of the Plasmodium falcipurum VAR2CSA protein · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q6UDW7
- Elsewhere: RCSB PDB 3CML · PDBe 3CML · UniProt Q6UDW7
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