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Crystal structure of a tetr family transcriptional regulator from pseudomonas syringae pv. tomato str. DC3000

Analyse Crystal structure of a tetr family transcriptional regulator from pseudomonas… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CDL
Type: protein
Length: 375 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Transcriptional regulator aefr
UniProt: Q87Z81
Pockets: 2 · best druggability 0.77

Structure

x-ray diffraction · 2 distinct chains · 71% helix, 1% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Transcriptional regulator aefr	protein	187	71% helix, 1% strand	Q87Z81
B	Transcriptional regulator aefr	protein	188	72% helix, 1% strand	Q87Z81

Pockets

2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1004	0.77	0.79	85	empty
2	233	0.53	0.77	29	empty

Interfaces

1 interface between chains.

A–B · 1542 Å² buried · 9 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 10 modified (engineered).

Compared structures

3CDL · Crystal structure of a TetR family transcriptional regulator from Pseudomonas syringae… · the same entry in another collection · chain A against A, TM-score 1.00

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Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q87Z81
Elsewhere: RCSB PDB 3CDL · PDBe 3CDL · UniProt Q87Z81

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