Research workbench
Crystal structure of the marr family transcriptional regulator SPO1453 from silicibacter pomeroyi dss-3
Analyse Crystal structure of the marr family transcriptional regulator SPO1453 from… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3CDH
- Type
- protein
- Length
- 270 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Transcriptional regulator, marr family
- UniProt
- Q5LTG1
- Ligands
- SO4
- Pockets
- 4 · best druggability 0.68
Structure
x-ray diffraction · 2 distinct chains · 73% helix, 6% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Transcriptional regulator, marr family | protein | 134 | 71% helix, 5% strand | Q5LTG1 |
| B | Transcriptional regulator, marr family | protein | 136 | 74% helix, 7% strand | Q5LTG1 |
Ligands and binding sites
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
4 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 52 | 0.68 | 0.96 | 16 | GOL |
| 2 | 305 | 0.61 | 0.78 | 32 | GOL |
| 3 | 60 | 0.46 | 0.83 | 13 | empty |
| 4 | 69 | 0.32 | 0.75 | 24 | empty |
Interfaces
1 interface between chains.
- A–B · 2509 Ų buried · 12 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 10 modified (engineered).
Compared structures
- 3CDH · Crystal structure of the MarR family transcriptional regulator SPO1453 from Silicibacter… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5LTG1
- Elsewhere: RCSB PDB 3CDH · PDBe 3CDH · UniProt Q5LTG1
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