Research workbench

Structure of nnqqny as an insert in T7 endonuclease I

Analyse Structure of nnqqny as an insert in T7 endonuclease I in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CAE
Type: protein
Length: 1,320 residues
Chains: 10
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Endonuclease I
EC: 3.1.21.2
UniProt: P00641
Pockets: 15 · best druggability 0.70

Structure

x-ray diffraction · 1 distinct chain · 30% helix, 27% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B, C, D, E, F, G, H, I, J	Endonuclease I (EC 3.1.21.2)	protein	132	30% helix, 27% strand	P00641

Pockets

15 pockets found on a 1 Å grid, 8 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	715	0.70	0.77	67	empty
2	720	0.69	0.76	63	empty
3	592	0.69	0.78	66	empty
4	589	0.67	0.77	57	empty
5	589	0.66	0.76	62	empty

Interfaces

22 interfaces between chains.

G–H · 3432 Å² buried · 61 hydrogen bonds · protein-protein
A–B · 3418 Å² buried · 60 hydrogen bonds · protein-protein
C–D · 3351 Å² buried · 65 hydrogen bonds · protein-protein
E–F · 3345 Å² buried · 65 hydrogen bonds · protein-protein
I–J · 3310 Å² buried · 63 hydrogen bonds · protein-protein

Compared structures

3CAE · Structure of NNQQNY as an insert in T7 endonuclease I · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00641
Elsewhere: RCSB PDB 3CAE · PDBe 3CAE · UniProt P00641

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.