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Crystal structure of natural killer cell receptor, LY49G

Analyse Crystal structure of natural killer cell receptor, LY49G in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3CAD
Type: protein
Length: 248 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Lectin-related nk cell receptor LY49G1
UniProt: Q9JHV6
Pockets: 7 · best druggability 0.64

Structure

x-ray diffraction · 2 distinct chains · 15% helix, 34% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Lectin-related nk cell receptor LY49G1	protein	123	13% helix, 33% strand	Q9JHV6
B	Lectin-related nk cell receptor LY49G1	protein	125	16% helix, 35% strand	Q9JHV6

Pockets

7 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	238	0.64	0.82	27	empty
2	71	0.63	0.91	22	empty
3	155	0.56	0.81	26	empty
4	311	0.55	0.76	46	empty
5	88	0.46	0.80	15	empty

Interfaces

1 interface between chains.

A–B · 509 Å² buried · 5 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 8 disulfide (disulfide).

Compared structures

3CAD · Crystal structure of Natural Killer Cell Receptor, Ly49G · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9JHV6
Elsewhere: RCSB PDB 3CAD · PDBe 3CAD · UniProt Q9JHV6

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