Research workbench
Crystal structure of the putative nitrite reductase NADPH (small subunit) oxidoreductase protein Q87HB1. northeast structural genomics consortium target VPR162
Analyse Crystal structure of the putative nitrite reductase NADPH (small subunit)… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3C0D
- Type
- protein
- Length
- 852 residues
- Chains
- 8
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Putative nitrite reductase NADPH (small subunit) oxidoreductase protein
- UniProt
- Q87HB1
- Pockets
- 7 · best druggability 0.71
Structure
x-ray diffraction · 3 distinct chains · 6% helix, 49% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Putative nitrite reductase NADPH (small subunit) oxidoreductase protein | protein | 109 | 6% helix, 50% strand | Q87HB1 |
| B | Putative nitrite reductase NADPH (small subunit) oxidoreductase protein | protein | 107 | 6% helix, 50% strand | Q87HB1 |
| C, D, E, F, G, H | Putative nitrite reductase NADPH (small subunit) oxidoreductase protein | protein | 106 | 6% helix, 46% strand | Q87HB1 |
Pockets
7 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 749 | 0.71 | 0.77 | 58 | empty |
| 2 | 162 | 0.53 | 0.79 | 26 | empty |
| 3 | 245 | 0.50 | 0.75 | 38 | empty |
| 4 | 87 | 0.45 | 0.80 | 24 | empty |
| 5 | 74 | 0.40 | 0.79 | 21 | empty |
Interfaces
11 interfaces between chains.
- C–H · 421 Ų buried · 4 hydrogen bonds · protein-protein
- C–F · 393 Ų buried · 6 hydrogen bonds · protein-protein
- B–G · 371 Ų buried · 4 hydrogen bonds · protein-protein
- A–C · 362 Ų buried · 0 hydrogen bonds · protein-protein
- B–F · 353 Ų buried · 0 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 24 modified (engineered).
Compared structures
- 3C0D · Crystal structure of the putative nitrite reductase NADPH (small subunit) oxidoreductase… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q87HB1
- Elsewhere: RCSB PDB 3C0D · PDBe 3C0D · UniProt Q87HB1
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.