Research workbench
Model of actin-fimbrin ABD2 complex
Analyse Model of actin-fimbrin ABD2 complex in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3BYH
- Type
- protein
- Length
- 605 residues
- Chains
- 2
- Method
- electron microscopy
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Actin; Fimbrin ABD2
- UniProt
- Q1KLZ0
- Pockets
- 6 · best druggability 0.76
Structure
electron microscopy · 2 distinct chains · 48% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Actin | protein | 374 | 40% helix, 20% strand | Q1KLZ0 |
| B | Fimbrin ABD2 | protein | 231 | 61% helix, 0% strand | — |
Pockets
6 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 766 | 0.76 | 0.80 | 81 | empty |
| 2 | 657 | 0.68 | 0.76 | 49 | empty |
| 3 | 251 | 0.58 | 0.79 | 40 | empty |
| 4 | 144 | 0.51 | 0.79 | 26 | empty |
| 5 | 127 | 0.44 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 949 Ų buried · 47 hydrogen bonds · protein-protein
Compared structures
- 3BYH · Model of actin-fimbrin ABD2 complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q1KLZ0
- Elsewhere: RCSB PDB 3BYH · PDBe 3BYH · UniProt Q1KLZ0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.