Research workbench
T5 5'-exonuclease
Analyse T5 5'-exonuclease in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1EXN
- Type
- protein
- Length
- 543 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 5'-exonuclease
- EC
- 3.1.11.3
- UniProt
- P06229
- Pockets
- 2 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 60% helix, 13% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 5'-exonuclease (EC 3.1.11.3) | protein | 271 | 60% helix, 11% strand | P06229 |
| B | 5'-exonuclease (EC 3.1.11.3) | protein | 272 | 60% helix, 14% strand | P06229 |
Pockets
2 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 523 | 0.67 | 0.78 | 57 | empty |
| 2 | 495 | 0.65 | 0.77 | 52 | empty |
Modifications
Observed in the structure: 8 modified (engineered).
Compared structures
- 1EXN · T5 5'-exonuclease · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P06229
- Elsewhere: RCSB PDB 1EXN · PDBe 1EXN · UniProt P06229
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