Research workbench
Crystal structure of regulatory protein tetr from rhodobacter sphaeroides
Analyse Crystal structure of regulatory protein tetr from rhodobacter sphaeroides in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3BRU
- Type
- protein
- Length
- 380 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Regulatory protein, tetr family
- UniProt
- Q3J6K8
- Pockets
- 3 · best druggability 0.67
Structure
x-ray diffraction · 2 distinct chains · 75% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Regulatory protein, tetr family | protein | 191 | 75% helix, 0% strand | Q3J6K8 |
| B | Regulatory protein, tetr family | protein | 189 | 75% helix, 0% strand | Q3J6K8 |
Pockets
3 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 305 | 0.67 | 0.82 | 24 | empty |
| 2 | 196 | 0.66 | 0.84 | 25 | empty |
| 3 | 54 | 0.35 | 0.78 | 12 | empty |
Interfaces
1 interface between chains.
- A–B · 1937 Ų buried · 23 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 6 modified (engineered).
Compared structures
- 3BRU · Crystal structure of regulatory protein TetR from Rhodobacter sphaeroides · the same entry in another collection · chain A against A, TM-score 1.00
- Q3J6K8 · AlphaFold monomer V2.0 prediction for transcriptional regulator acur (Q3J6K8) · a predicted model of the same protein · chain B against A, TM-score 0.99
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q3J6K8
- Elsewhere: RCSB PDB 3BRU · PDBe 3BRU · UniProt Q3J6K8
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