Crystal structure of the mouse pd-1 and pd-L2 complex

Structure

x-ray diffraction · 2 distinct chains · 6% helix, 55% strand (DSSP).

Ligands and binding sites

• GOL · Glycerol · additive · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Interfaces

1 interface between chains.

• A–B · 1010 Ų buried · 21 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 4 disulfide (disulfide).

Compared structures

• 3BP5 · Crystal structure of the mouse PD-1 and PD-L2 complex · the same entry in another collection · chain A against A, TM-score 1.00
• Q02242 · AlphaFold monomer V2.0 prediction for programmed cell death protein 1 (Q02242) · a predicted model of the same protein · chain A against A, TM-score 0.98
• Q9WUL5 · AlphaFold monomer V2.0 prediction for programmed cell death 1 ligand 2 (Q9WUL5) · a predicted model of the same protein · chain B against A, TM-score 0.96

Analyse

• Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
• Every structure of UniProt Q02242
• Every structure of UniProt Q9WUL5
• Elsewhere: RCSB PDB 3BP5 · PDBe 3BP5 · UniProt Q02242 · UniProt Q9WUL5