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Crystal structure of DNA restriction endonuclease naei
Analyse Crystal structure of DNA restriction endonuclease naei in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 1EV7
- Type
- protein
- Length
- 588 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Type iie restriction endonuclease naei
- EC
- 3.1.21.4
- UniProt
- P50187
- Pockets
- 6 · best druggability 0.73
Structure
x-ray diffraction · 2 distinct chains · 36% helix, 19% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Type iie restriction endonuclease naei (EC 3.1.21.4) | protein | 295 | 34% helix, 19% strand | P50187 |
| B | Type iie restriction endonuclease naei (EC 3.1.21.4) | protein | 293 | 37% helix, 20% strand | P50187 |
Pockets
6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 828 | 0.73 | 0.78 | 56 | empty |
| 2 | 976 | 0.71 | 0.76 | 93 | empty |
| 3 | 58 | 0.40 | 0.81 | 14 | empty |
| 4 | 121 | 0.40 | 0.75 | 20 | empty |
| 5 | 85 | 0.37 | 0.76 | 18 | empty |
Interfaces
1 interface between chains.
- A–B · 1297 Ų buried · 24 hydrogen bonds · protein-protein
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P50187
- Elsewhere: RCSB PDB 1EV7 · PDBe 1EV7 · UniProt P50187
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