Research workbench
Crystal structure of unknown function protein EF1359
Analyse Crystal structure of unknown function protein EF1359 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3B48
- Type
- protein
- Length
- 790 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Uncharacterized protein
- UniProt
- Q835L8
- Pockets
- 5 · best druggability 0.77
Structure
x-ray diffraction · 6 distinct chains · 46% helix, 15% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Uncharacterized protein | protein | 129 | 47% helix, 15% strand | Q835L8 |
| B | Uncharacterized protein | protein | 132 | 44% helix, 16% strand | Q835L8 |
| C | Uncharacterized protein | protein | 134 | 45% helix, 16% strand | Q835L8 |
| D | Uncharacterized protein | protein | 130 | 47% helix, 15% strand | Q835L8 |
| E | Uncharacterized protein | protein | 130 | 47% helix, 15% strand | Q835L8 |
| F | Uncharacterized protein | protein | 135 | 45% helix, 15% strand | Q835L8 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 913 | 0.77 | 0.80 | 84 | empty |
| 2 | 82 | 0.47 | 0.82 | 17 | empty |
| 3 | 98 | 0.46 | 0.80 | 15 | empty |
| 4 | 55 | 0.41 | 0.82 | 14 | empty |
| 5 | 53 | 0.34 | 0.79 | 17 | empty |
Interfaces
9 interfaces between chains.
- A–B · 1619 Ų buried · 20 hydrogen bonds · protein-protein
- E–F · 1489 Ų buried · 19 hydrogen bonds · protein-protein
- C–D · 1392 Ų buried · 15 hydrogen bonds · protein-protein
- A–C · 446 Ų buried · 0 hydrogen bonds · protein-protein
- A–E · 263 Ų buried · 2 hydrogen bonds · protein-protein
Modifications
Observed in the structure: 36 modified (engineered).
Compared structures
- 3B48 · Crystal structure of unknown function protein EF1359 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q835L8
- Elsewhere: RCSB PDB 3B48 · PDBe 3B48 · UniProt Q835L8
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