Research workbench
Structural and biochemical characterization of CLFB:LIGAND interactions
Analyse Structural and biochemical characterization of CLFB:LIGAND interactions in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3AT0
- Type
- protein
- Length
- 329 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Clumping factor B; C-terminal alpha chain peptide
- UniProt
- Q7A382, P02671
- Pockets
- 1 · best druggability 0.59
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 50% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Clumping factor B | protein | 317 | 6% helix, 50% strand | Q7A382 |
| B | C-terminal alpha chain peptide | protein | 12 | 0% helix, 42% strand | P02671 |
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 269 | 0.59 | 0.79 | 36 | empty |
Interfaces
1 interface between chains.
- A–B · 760 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 3AT0 · Structural and biochemical characterization of ClfB:ligand interactions · the same entry in another collection · chain A against A, TM-score 1.00
- Q7A382 · AlphaFold monomer V2.0 prediction for clumping factor B (Q7A382) · a predicted model of the same protein · chain A against A, TM-score 0.98
- P02671 · AlphaFold monomer V2.0 prediction for fibrinogen alpha chain (P02671) · a predicted model of the same protein · chain B against A, TM-score 0.50
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q7A382
- Every structure of UniProt P02671
- Elsewhere: RCSB PDB 3AT0 · PDBe 3AT0 · UniProt Q7A382 · UniProt P02671
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