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Crystal structure of serine dehydrogenase from escherichia COLI
Analyse Crystal structure of serine dehydrogenase from escherichia COLI in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.
- PDB
- 3ASU
- Type
- protein
- Length
- 434 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Short-chain DEHYDROGENASE/REDUCTASE sdr
- EC
- 1.1.1.276
- Pockets
- 4 · best druggability 0.48
Structure
x-ray diffraction · 2 distinct chains · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Short-chain DEHYDROGENASE/REDUCTASE sdr (EC 1.1.1.276) | protein | 218 | 45% helix, 17% strand | — |
| B | Short-chain DEHYDROGENASE/REDUCTASE sdr (EC 1.1.1.276) | protein | 216 | 45% helix, 16% strand | — |
Pockets
4 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 131 | 0.48 | 0.79 | 20 | empty |
| 2 | 175 | 0.46 | 0.75 | 27 | empty |
| 3 | 100 | 0.44 | 0.79 | 18 | empty |
| 4 | 145 | 0.41 | 0.74 | 29 | empty |
Interfaces
1 interface between chains.
- A–B · 1809 Ų buried · 35 hydrogen bonds · protein-protein
Compared structures
- 3ASU · Crystal structure of serine dehydrogenase from Escherichia coli · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Elsewhere: RCSB PDB 3ASU · PDBe 3ASU
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