Research workbench

Mama D159K mutant 2

Analyse Mama D159K mutant 2 in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 3ASG
Type: protein
Length: 352 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Mama
UniProt: Q50224
Pockets: 1 · best druggability 0.59

Structure

x-ray diffraction · 2 distinct chains · 77% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Mama	protein	182	76% helix, 0% strand	Q50224
B	Mama	protein	170	77% helix, 0% strand	Q50224

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	436	0.59	0.74	37	empty

Interfaces

1 interface between chains.

A–B · 325 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

3ASG · MamA D159K mutant 2 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q50224
Elsewhere: RCSB PDB 3ASG · PDBe 3ASG · UniProt Q50224

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